Description

3,7-Dihydroxy-20,22-Methylenecholan-23-Oic Acid is a high-purity, synthetic steroid derivative with a defined molecular structure. This compound serves as a critical intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and metabolic disease. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid hormone analogs and bile acid derivatives for therapeutic applications.
• Research Chemical: Used in academic and industrial research to study steroid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Biochemical Tool: Employed in biochemical assays to investigate enzyme inhibition or modulation related to cholesterol and bile acid metabolism.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create more complex, functionally advanced steroid molecules for various applications.

Basic Information

Product Name	3,7-Dihydroxy-20,22-Methylenecholan-23-Oic Acid
CAS No.	95498-96-7
Molecular Formula	C₂₅H₄₀O₄
Molecular Weight	404.59 g/mol
Synonyms	20,22-Methylene-3,7-dihydroxycholan-23-oic Acid; 23-Nor-5β-cholan-23-oic acid, 3,7-dihydroxy-20,22-methylen-, (3α,5β,7α,20R)-; 3α,7α-Dihydroxy-20,22-methylen-23-nor-5β-cholan-23-oic Acid; 20,22-Methylene lithocholic acid derivative; Steroid dihydroxy acid intermediate
EINECS	Contact for details

Quality Control

Our 3,7-Dihydroxy-20,22-Methylenecholan-23-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.