Description

5-Ethoxymethyluridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of novel oligonucleotides and prodrugs, enabling the fine-tuning of pharmacokinetic properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, mRNA-based therapeutics, and other cutting-edge biotechnologies.

Application

• Pharmaceutical Intermediate: A key synthon in the production of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a modified monomer to introduce specific functionalities into synthetic DNA/RNA strands for therapeutic and diagnostic applications.
• Prodrug Development: Acts as a promoiety to enhance the bioavailability and targeted delivery of active pharmaceutical ingredients.
• Biochemical Research: Employed in studies investigating nucleic acid metabolism, enzyme mechanisms, and structure-activity relationships.
• Antiviral Agent Research: Investigated for its potential direct activity or as a precursor in the development of compounds against viral pathogens.
• Labeled Compound Synthesis: Serves as a starting material for the preparation of isotopically labeled (e.g., 13C, 15N) nucleosides for metabolic tracing studies.

Basic Information

Product Name	5-Ethoxymethyluridine
CAS No.	95468-92-1
Molecular Formula	C12H16N2O6
Molecular Weight	284.26 g/mol
Synonyms	5-(Ethoxymethyl)uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(ethoxymethyl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5-(ethoxymethyl)-; 5-EMU; 5-Ethoxymethyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Ethoxymethyluridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.