Description

4,5,6,7-Tetrahydro-1-benzothiophene-3-carbonyl chloride is a versatile and highly reactive chemical intermediate, primarily used as a key building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the tetrahydrobenzothiophene pharmacophore, a crucial structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and polymers.
• Chemical Biology: Employed as a probe or linker in the design of enzyme inhibitors and other bioactive tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring the construction of complex sulfur-containing heterocycles.

Basic Information

Product Name	4,5,6,7-Tetrahydro-1-benzothiophene-3-carbonyl chloride
CAS No.	95461-22-6
Molecular Formula	C10H9ClOS
Molecular Weight	212.69 g/mol
Synonyms	4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carbonyl chloride; 4,5,6,7-Tetrahydro-1-benzothiophene-3-carboxylic acid chloride; 3-Chlorocarbonyl-4,5,6,7-tetrahydrobenzo[b]thiophene; Tetrahydrobenzothiophene-3-carbonyl chloride; 4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carbonyl chloride; 3-Carboxy-4,5,6,7-tetrahydrobenzo[b]thiophene chloride
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-1-benzothiophene-3-carbonyl chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.