Description

2-Bromo-4-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-bromo-4-fluorobenzoyl moiety, enabling the construction of complex molecules with specific electronic and steric properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly in the creation of protease inhibitors, kinase inhibitors, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require halogenated aromatic structures for enhanced bioactivity.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating halogenated aromatic cores in advanced electronic and display materials.
• Polymer Chemistry: Employed in the synthesis of specialty monomers and polymers where the bromo and fluoro substituents modify material properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Peptide & Protein Modification: Can be used as an acylating agent for modifying amino acids or peptides to study structure-activity relationships.

Basic Information

Product Name	2-Bromo-4-Fluorobenzoyl Chloride
CAS No.	95383-36-1
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	4-Fluoro-2-bromobenzoyl chloride; 2-Bromo-4-fluorobenzoic acid chloride; Benzoic acid, 2-bromo-4-fluoro-, chloride; 2-Bromo-4-fluorobenzoyl chloride; 95383-36-1; 4-Fluoro-2-bromobenzoic acid chloride; 2-Bromo-4-fluorobenzoic chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.