Description

α-L-Fucopyranosylphenyl Isothiocyanate is a specialized glycosyl isothiocyanate derivative used as a critical building block in carbohydrate chemistry and glycobiology research. This compound serves as a key reagent for the chemoselective labeling and conjugation of biomolecules, enabling the study of complex glycan structures and interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for developing targeted probes, glycan arrays, and novel bioconjugates.

Application

• Glycoconjugate Synthesis: Acts as a versatile intermediate for the preparation of neoglycoconjugates, glycoproteins, and glycolipids.
• Biomolecular Labeling: Used for the site-specific fluorescent or affinity tagging of proteins, peptides, and other biomolecules via its reactive isothiocyanate group.
• Glycan Array Fabrication: Employed in the development of carbohydrate microarrays for high-throughput screening of protein-carbohydrate interactions.
• Enzyme Substrate & Inhibitor Development: Serves as a precursor for creating substrates or inhibitors for fucosidases and other glycosyltransferases.
• Diagnostic Reagent Production: Utilized in the synthesis of reagents for immunoassays and diagnostic kits targeting carbohydrate-based biomarkers.
• Chemical Biology Probes: Integral to the design of activity-based probes (ABPs) for profiling glycosidase activity in complex biological systems.

Basic Information

Product Name	α-L-Fucopyranosylphenyl Isothiocyanate
CAS No.	95344-14-2
Molecular Formula	C13H15NO5S
Molecular Weight	297.33 g/mol
Synonyms	Phenyl 1-Thio-α-L-fucopyranoside Isothiocyanate; 1-Isothiocyanato-1-deoxy-α-L-fucopyranosylbenzene; α-L-Fucopyranosyl Phenyl Isothiocyanate; L-Fucose Phenyl Isothiocyanate Derivative; Glycosyl Phenyl Isothiocyanate; Fucosyl Isothiocyanate; Carbohydrate Isothiocyanate Reagent
EINECS	Contact for details

Quality Control

Our α-L-Fucopyranosylphenyl Isothiocyanate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.