Description

9-Isothiocyanato-10-Methylacridinium Tri is a specialized cationic acridine derivative, primarily valued as a key intermediate and labeling reagent in advanced biochemical and pharmaceutical research. Its structure combines a reactive isothiocyanate group with a methylacridinium core, making it particularly useful for covalent conjugation to biomolecules. This compound is essential for researchers and manufacturers in the fields of fluorescent labeling, diagnostic assay development, and targeted drug delivery systems. Its unique properties support innovation in life sciences and high-purity chemical synthesis.

Application

• Fluorescent Probe Synthesis: Acts as a reactive precursor for creating fluorescent tags and markers used in bioimaging and cellular analysis.
• Diagnostic Reagent Intermediate: Used in the development of chemiluminescent or fluorescent immunoassays (CLIA/ELISA) for clinical diagnostics.
• Bioconjugation: The isothiocyanate group enables stable covalent bonding to proteins, antibodies, and peptides for creating targeted bioconjugates.
• Pharmaceutical Research: Serves as a building block in the synthesis of novel acridine-based therapeutic agents and drug candidates.
• Material Science: Can be utilized in the development of functionalized polymers and smart materials with specific optical properties.
• Analytical Chemistry: Employed as a derivatization agent in chromatography and spectrometry for detecting specific analytes.

Basic Information

Product Name	9-Isothiocyanato-10-Methylacridinium Tri
CAS No.	95256-52-3
Molecular Formula	C16H13N3S (as the cation; counterion may vary)
Molecular Weight	279.36 g/mol (for the cation)
Synonyms	10-Methyl-9-isothiocyanatoacridinium; 9-Isothiocyanato-10-methylacridinium; Acridinium, 9-isothiocyanato-10-methyl-; Methylacridinium isothiocyanate; Acridine Orange isothiocyanate derivative; Fluorescent acridine isothiocyanate; AIAT; Research Grade Acridine Labeling Reagent
EINECS	Contact for details

Quality Control

Our production of 9-Isothiocyanato-10-Methylacridinium Tri adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when possible and opened only in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.