Description

Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Chloro- (9Ci) is a specialized fluorinated organic building block characterized by its rigid bicyclic framework. This compound matters as a high-value intermediate for advanced synthesis, offering a unique combination of steric bulk and reactivity for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing the bicyclo[2.2.2]octane scaffold.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides, where its structural motif can enhance biological activity and stability.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and other advanced functional materials requiring rigid, three-dimensional components.
• Organic Synthesis Building Block: Acts as a versatile precursor for further functionalization via the reactive carbonyl fluoride group, enabling the synthesis of amides, esters, and other derivatives.
• Fluorine Chemistry Studies: Utilized in academic and industrial research focused on the properties and reactivities of organofluorine compounds.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Chloro- (9Ci)
CAS No.	94994-06-6
Molecular Formula	C9H10ClFO
Molecular Weight	188.63 g/mol
Synonyms	4-Chlorobicyclo[2.2.2]octane-1-carbonyl fluoride; 4-Chloro-1-(fluorocarbonyl)bicyclo[2.2.2]octane; 1-Carbonyl fluoride-4-chlorobicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-carbonyl fluoride, 4-chloro-; 4-Chloroadamantane-1-carbonyl fluoride (common misnomer based on structure); 4-Chloro-tricyclo[3.3.1.1³,⁷]decane-1-carbonyl fluoride (systematic alternative); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-1-Carbonyl Fluoride, 4-Chloro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC/GC), impurity profile, and physical characteristics are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) and highly volatile nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.