Description

4-Isoquinolinecarbonyl Chloride, 1,2-Dihydro-1-Oxo- (9Ci) is a specialized heterocyclic acid chloride derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its high reactivity, enabling the efficient introduction of the 1-oxo-1,2-dihydroisoquinoline-4-carbonyl moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of potential drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection and pest management.
• Material Science: Building block for creating specialized polymers or organic electronic materials with unique properties.
• Academic & R&D: Fundamental reagent in heterocyclic chemistry research for studying reaction mechanisms and developing new synthetic methodologies.
• Chemical Biology: Potential use in creating molecular probes or affinity tags for studying biological systems.

Basic Information

Product Name	4-Isoquinolinecarbonyl Chloride, 1,2-Dihydro-1-Oxo- (9Ci)
CAS No.	94974-61-5
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	1,2-Dihydro-1-oxo-4-isoquinolinecarbonyl chloride; 1-Oxo-1,2-dihydroisoquinoline-4-carbonyl chloride; 4-Carboxyisoquinolin-1(2H)-one chloride; 1-Oxo-1,2-dihydro-4-isoquinolinecarboxylic acid chloride; 1,2-Dihydro-1-oxoisoquinoline-4-carbonyl chloride; 4-(Chlorocarbonyl)-1(2H)-isoquinolinone; 1-Hydroxy-4-isoquinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Isoquinolinecarbonyl Chloride, 1,2-Dihydro-1-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	95.0 - 105.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.