Description

2'-Deoxy-2'-Fluoro-5-Hydroxymethyl Arabinouridine is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based drugs. The product is supplied with a high level of purity to meet the stringent requirements of modern medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies and drug candidate optimization.
• Antiviral Drug Development: Investigated for its potential incorporation into prodrugs targeting viral polymerases.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Process Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-5-Hydroxymethyl Arabinouridine
CAS No.	94817-51-3
Molecular Formula	C10H13FN2O6
Molecular Weight	276.22 g/mol
Synonyms	2'-Deoxy-2'-fluoro-5-(hydroxymethyl)arabinouridine; 2'-F-5-HMAU; 2'-Fluoro-2'-deoxy-5-hydroxymethylarabinouridine; 5-Hydroxymethyl-2'-deoxy-2'-fluorouridine; 2'-Fluoro-5-hydroxymethyl-2'-deoxyuridine; 2'-F-ara-5-HMU; 94817-51-3; 2'-Deoxy-2'-fluoro-5-(hydroxymethyl)-1-β-D-arabinofuranosyluracil
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-5-Hydroxymethyl Arabinouridine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material suitable for research and development purposes, with specifications aligned with industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.