Description

2-Pyrrolidinecarbonyl Chloride, 1-Methyl- (9Ci) is a versatile and highly reactive organic intermediate, primarily used as a key building block in advanced chemical synthesis. Its value lies in its ability to efficiently introduce the 1-methylpyrrolidine-2-carbonyl moiety, a structural motif of significant interest in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrrolidine or proline derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Peptide Mimetics & Drug Discovery: Facilitates the creation of peptidomimetics and novel molecular scaffolds in medicinal chemistry research programs.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Pyrrolidinecarbonyl Chloride, 1-Methyl- (9Ci)
CAS No.	94813-61-3
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	1-Methylpyrrolidine-2-carbonyl chloride; N-Methylprolyl chloride; 1-Methyl-L-proline chloride; N-Methyl-L-proline chloride; (S)-1-Methylpyrrolidine-2-carbonyl chloride; (S)-N-Methylprolyl chloride; L-N-Methylprolyl chloride; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbonyl Chloride, 1-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay and impurity profiles to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, it should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.