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3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-D-Glucose CAS NO 94715-66-9
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CAS No.:94715-66-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-D-Glucose is a key protected monosaccharide derivative, widely utilized as a versatile synthetic intermediate in carbohydrate chemistry. Its value lies in the strategic protection of hydroxyl groups and the presence of a reactive azido functionality, enabling precise glycosylation and click chemistry reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the synthesis of nucleoside analogs, glycoconjugates, and complex oligosaccharides.
Application
- Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside drugs.
- Glycobiology Research: Used in the preparation of glycopeptides, glycolipids, and other biologically active glycoconjugates for drug discovery.
- Click Chemistry Substrate: The azido group facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer modification.
- Oligosaccharide Synthesis: Serves as a key glycosyl donor or acceptor in the stepwise construction of complex carbohydrate structures.
- Chemical Biology Probes: Enables the development of metabolic labeling probes to study glycosylation pathways in living systems.
- Material Science: Used to create functionalized surfaces and smart polymeric materials with specific biological recognition properties.
Basic Information
| Product Name | 3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-D-Glucose |
| CAS No. | 94715-66-9 |
| Molecular Formula | C₁₂H₁₇N₃O₈ |
| Molecular Weight | 331.28 g/mol |
| Synonyms | 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-D-glucopyranose; 2-Azido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranose; 3,4,6-Tri-O-acetyl-2-azido-2-deoxy-D-glucopyranose; 2-Azido-2-deoxy-1,3,4,6-tetra-O-acetyl-D-glucopyranose (tautomer); Acetylated Azido Glucose; D-Glucose, 2-azido-2-deoxy-, 3,4,6-triacetate |
| EINECS | Contact for details |
Quality Control
Our 3,4,6-Tri-o-Acetyl-2-Azido-2-Deoxy-D-Glucose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with major pharmacopeial standards and can provide material suitable for advanced pharmaceutical applications upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Specific Rotation | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Impurity (HPLC) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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