Description

3-β-Ribofuranosylthieno(2,3-D)Pyrimidin-4-One is a specialized nucleoside analogue, a key building block in medicinal chemistry and pharmaceutical research. This compound is valued for its role as a precursor in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular enzymes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of nucleoside-based antiviral drugs and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving polymerases and kinases.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Antiviral Drug Development: Key building block for potential therapeutics targeting viruses such as hepatitis and herpes.
• Oncology Research: Investigated for the development of novel compounds that interfere with DNA/RNA synthesis in cancer cells.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of high-value, complex organic molecules.

Basic Information

Product Name	3-β-Ribofuranosylthieno(2,3-D)Pyrimidin-4-One
CAS No.	94644-73-2
Molecular Formula	C11H12N2O5S
Molecular Weight	284.29 g/mol
Synonyms	4-Oxo-3-β-D-ribofuranosylthieno[2,3-d]pyrimidine; 3-β-D-Ribofuranosylthieno[2,3-d]pyrimidin-4(3H)-one; Thieno[2,3-d]pyrimidin-4-one, 3-β-D-ribofuranosyl-; 3-β-D-Ribofuranosylthieno[2,3-d]pyrimidin-4-one; 3-β-D-Ribofuranosylthieno[2,3-d]pyrimidin-4-one; NSC 401005; Thienopyrimidine nucleoside
EINECS	Contact for details

Quality Control

Our 3-β-Ribofuranosylthieno(2,3-D)Pyrimidin-4-One is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.