Description

[23R,24R,(-)]-23,24-Methanocholest-5-En-3β-Ol is a high-purity, synthetic sterol derivative characterized by a unique methano-bridged side chain. This compound serves as a critical chiral intermediate and reference standard in advanced pharmaceutical research and fine chemical synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-fidelity building blocks for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel steroid-based therapeutics and hormone analogs.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Employed in studies of sterol metabolism, enzyme inhibition assays, and investigations into lipid membrane properties.
• Fine Chemical Synthesis: Serves as a sophisticated starting material or intermediate for the synthesis of complex, high-value specialty chemicals.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	[23R,24R,(-)]-23,24-Methanocholest-5-En-3β-Ol
CAS No.	94595-29-6
Molecular Formula	C₂₈H₄₈O
Molecular Weight	400.68 g/mol
Synonyms	(-)-23,24-Methanocholest-5-en-3β-ol; (23R,24R)-23,24-Methanocholest-5-en-3β-ol; 23,24-Methanocholest-5-en-3-ol, (3β,23R,24R)-; 3β-Hydroxy-(23R,24R)-23,24-methanocholest-5-ene; Methanocholestrol derivative; Sterol methano-bridge analog
EINECS	Contact for details

Quality Control

Our [23R,24R,(-)]-23,24-Methanocholest-5-En-3β-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.