Description

Pyridine 1,N(6)-Ethenoadenine Dinucleotide is a specialized biochemical cofactor analog, a modified form of nicotinamide adenine dinucleotide (NAD+). This compound is of significant interest in biochemical and pharmacological research due to its role as a mechanism-based inhibitor and probe for NAD+-dependent enzymes, particularly dehydrogenases. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for studying enzyme kinetics, metabolic pathways, and developing targeted therapeutic agents.

Application

• Enzymology Research: As a potent inhibitor for mechanistic studies of NAD(P)+-dependent dehydrogenases and other oxidoreductases.
• Drug Discovery: Serves as a tool compound for screening and validating novel inhibitors targeting specific metabolic enzymes in cancer and infectious diseases.
• Metabolic Pathway Analysis: Used to probe and modulate cellular redox states and metabolic flux in biochemical assays.
• Diagnostic Reagent Development: A key component in the formulation of specialized assay kits for clinical and research laboratories.
• Biochemical Tool Manufacturing: Supplied to producers of high-purity biochemicals and research reagents.
• Academic Research: Employed in university and institutional labs for fundamental studies in biochemistry and molecular biology.

Basic Information

Product Name	Pyridine 1,N(6)-Ethenoadenine Dinucleotide
CAS No.	94516-25-3
Molecular Formula	C₂₂H₂₈N₇O₁₄P₂
Molecular Weight	700.45 g/mol
Synonyms	1,N(6)-Etheno-NAD+; ε-NAD+; Ethenoadenine NAD+; Pyridine Adenine Dinucleotide Etheno Adduct; 1,N6-Ethenonicotinamide Adenine Dinucleotide; Etheno-NAD; NAD Etheno Adduct; Research Grade ε-NAD
EINECS	Contact for details

Quality Control

Our Pyridine 1,N(6)-Ethenoadenine Dinucleotide is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research biochemicals, and specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.