Description

(11Beta,16Beta)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride is a high-purity synthetic corticosteroid derivative, valued for its potent anti-inflammatory and immunosuppressive pharmacological activity. This compound is critical for pharmaceutical research and development, particularly in the formulation of advanced topical and systemic steroid medications. It serves as a key active pharmaceutical ingredient (API) or advanced intermediate for manufacturers and R&D laboratories in the global pharmaceutical and life sciences sectors.

Application

• Pharmaceutical API Intermediate: A crucial building block in the synthesis of potent topical corticosteroids for treating dermatological conditions like eczema, psoriasis, and dermatitis.
• Anti-inflammatory Drug Research: Used in preclinical and clinical research to study mechanisms of action and efficacy of new steroid-based therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory compliance testing in pharmaceutical manufacturing.
• Formulation Development: Employed in the development of creams, ointments, and other dosage forms requiring a potent glucocorticoid receptor agonist.
• Biochemical Research: Utilized in laboratory studies to investigate steroid hormone pathways, receptor binding, and cellular signaling processes.

Basic Information

Product Name	(11Beta,16Beta)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride
CAS No.	94237-33-9
Molecular Formula	C₂₈H₃₉ClFNO₆
Molecular Weight	540.07 g/mol
Synonyms	Flumethasone Pivalate Impurity; Flumethasone Pivalate Related Compound; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(diethylamino)acetate hydrochloride; (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl 2-(diethylamino)acetate hydrochloride; Flumetasone pivalate EP Impurity B; Flumethasone pivalate impurity B (EP); Desoxymetasone pivalate impurity; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (11Beta,16Beta)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.