Description

6-Chloropurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified nucleotide analog of significant interest in biochemical and pharmacological research. This compound serves as a valuable tool for studying cyclic nucleotide-dependent signaling pathways and enzyme mechanisms, particularly those involving phosphodiesterases and protein kinases. It is primarily utilized by researchers and developers in the fields of life sciences, pharmaceutical R&D, and biotechnology for investigating cellular regulation and developing novel therapeutic agents.

Application

• Biochemical Research: As a substrate or inhibitor in enzymatic assays to study the activity and kinetics of phosphodiesterases (PDEs).
• Cell Signaling Studies: Investigation of intracellular signaling cascades mediated by cyclic nucleotides (cAMP/cGMP analogs).
• Pharmaceutical Development: A key intermediate or reference standard in the synthesis and screening of novel purine-based therapeutics targeting various diseases.
• Molecular Biology: Tool compound for probing adenosine receptor signaling and nucleotide metabolism in cellular models.
• Academic Research: Used in university and institutional labs for fundamental research in enzymology and signal transduction.

Basic Information

Product Name	6-Chloropurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	94200-58-5
Molecular Formula	C11H11ClN5O7P•Na
Molecular Weight	417.65 g/mol
Synonyms	6-Chloro-9-β-D-ribofuranosylpurine 3',5'-cyclic monophosphate sodium salt; 6-Chloropurine riboside cyclic 3',5'-monophosphate sodium salt; 6-Cl-cPuMP sodium salt; 6-Chloropurine cyclic nucleotide sodium salt; Sodium 6-chloro-9-(β-D-ribofuranosyl)purine-3',5'-cyclic monophosphate; cPuMP-6-Cl Na; 6-Chloro-cPuMP Na
EINECS	Contact for details

Quality Control

Our 6-Chloropurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.