Description

Methyl 3-(Chlorocarbonyl)Thiazolidine-4-Carboxylate is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a reactive scaffold for further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of thiazolidine-based drug candidates, including potential protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with thiazolidine cores.
• Peptidomimetics Research: Serves as a constrained scaffold in medicinal chemistry for creating peptide analogs with improved metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific thiazolidine carboxylic acid derivatives.

Basic Information

Product Name	Methyl 3-(Chlorocarbonyl)Thiazolidine-4-Carboxylate
CAS No.	94134-48-2
Molecular Formula	C6H8ClNO3S
Molecular Weight	209.65 g/mol
Synonyms	Methyl 3-(chloroformyl)-1,3-thiazolidine-4-carboxylate; 4-Thiazolidinecarboxylic acid, 3-(chlorocarbonyl)-, methyl ester; Methyl 3-carbamoylthiazolidine-4-carboxylate hydrochloride precursor; Thiazolidine-4-carboxylic acid, 3-(chlorocarbonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(Chlorocarbonyl)Thiazolidine-4-Carboxylate is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.