Description

9-(1,3-Dihydroxy-2-Propoxymethyl)-Gmp is a high-purity nucleotide derivative with significant importance in pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for advanced drug discovery programs and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analog antiviral drugs.
• Antiviral Drug Development: Research and production of compounds targeting herpesviruses, hepatitis viruses, and other viral pathogens.
• Anticancer Agent Synthesis: Building block for developing nucleotide-based chemotherapeutic agents.
• Biochemical Research: Used in enzymatic studies and as a substrate analog for polymerase research.
• Prodrug Synthesis: Intermediate for creating more bioavailable prodrug forms of nucleotide therapeutics.
• Labeled Compound Production: Basis for synthesizing isotopically labeled compounds for metabolic and pharmacokinetic studies.

Basic Information

Product Name	9-(1,3-Dihydroxy-2-Propoxymethyl)-Gmp
CAS No.	93824-31-8
Molecular Formula	C14H21N5O9P
Molecular Weight	443.32 g/mol
Synonyms	9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine monophosphate; Ganciclovir monophosphate; 9-(1,3-Dihydroxy-2-propoxy)methylguanine 5'-monophosphate; 9-[(2-Propoxy-1,3-dihydroxy)methyl]GMP; GMP, 9-[(1,3-dihydroxy-2-propoxy)methyl]-; NSC 113939; BIOLF-62; GCV-MP
EINECS	Contact for details

Quality Control

Our 9-(1,3-Dihydroxy-2-Propoxymethyl)-Gmp is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.