Description

3-Chloro-2-Hydroxybenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive acyl chloride group and a phenolic hydroxyl, makes it indispensable for constructing complex molecular architectures. This high-purity intermediate is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobial agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its halogenated benzoyl structure.
• Dye and Pigment Manufacturing: Acts as a coupling agent and intermediate for creating azo dyes and high-performance pigments.
• Polymer Chemistry: Serves as a monomer or modifier for engineering plastics, liquid crystal polymers (LCPs), and specialty polyesters.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and material properties.
• Ligand and Chelating Agent Synthesis: Useful for preparing complexing agents used in catalysis and metal extraction processes.

Basic Information

Product Name	3-Chloro-2-Hydroxybenzoyl Chloride
CAS No.	93820-08-7
Molecular Formula	C7H4Cl2O2
Molecular Weight	191.01 g/mol
Synonyms	2-Hydroxy-3-chlorobenzoyl chloride; 3-Chlorosalicyloyl chloride; 3-Chloro-2-hydroxybenzoic acid chloride; 3-Chloro-2-hydroxybenzoyl chloride; 3-Chlorosalicylic acid chloride; 3-Chloro-2-hydroxybenzenecarbonyl chloride; 3-Chloro-2-hydroxybenzene-1-carbonyl chloride; 3-Chloro-2-carboxyphenyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Hydroxybenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.