Description

2'-Deoxyinosine 3'-Benzoate is a chemically modified nucleoside derivative, specifically a benzoate ester of deoxyinosine. This compound is a crucial building block and key intermediate in the synthesis of complex oligonucleotides and modified nucleic acids, enabling precise control over molecular structure and function. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced drug discovery, oligonucleotide therapeutics development, and biochemical research.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
• Antiviral & Anticancer Drug Development: Serves as a critical intermediate in the research and production of nucleoside analog prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and repair pathways.
• Proteomics & Genomics: Employed in the preparation of labeled probes and primers for advanced diagnostic assays and sequencing.
• Academic Research: A valuable tool for studying the structure-activity relationships (SAR) of nucleosides and their impact on biological systems.
• Pharmaceutical Intermediates: Manufacture of high-value Active Pharmaceutical Ingredients (APIs) for targeted therapies.

Basic Information

Product Name	2'-Deoxyinosine 3'-Benzoate
CAS No.	93778-58-6
Molecular Formula	C₁₆H₁₆N₄O₆
Molecular Weight	360.32 g/mol
Synonyms	2'-Deoxyinosine 3'-monobenzoate; 9-[(2R,4S,5R)-4-(Benzoyloxy)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; Inosine, 2'-deoxy-, 3'-benzoate; 3'-O-Benzoyl-2'-deoxyinosine; 2'-Deoxy-3'-O-benzoylinosine; dI(Bz)
EINECS	Contact for details

Quality Control

Our 2'-Deoxyinosine 3'-Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.