Description

Hydroxy-[4-(4-Hydroxy-3,5-Diiodo-Phenoxy)]-3,5-Diiodophenylacetic Acid is a high-purity iodinated phenolic compound, a key intermediate in the synthesis of specialized pharmaceuticals and diagnostic agents. Its precise molecular architecture, featuring multiple iodine atoms, is critical for applications requiring high atomic number contrast agents or thyroid hormone analogs. This compound is essential for research and manufacturing in the pharmaceutical, biotechnology, and advanced diagnostic imaging sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of thyroid hormone analogs (e.g., levothyroxine derivatives) and other iodinated active pharmaceutical ingredients (APIs).
• Contrast Agent Precursor: Used in the research and development of X-ray and computed tomography (CT) contrast media due to its high iodine content.
• Biochemical Research: Serves as a specialized reagent in biochemical studies involving iodine metabolism, receptor binding assays, and hormone action pathways.
• Diagnostic Probe Development: Utilized in creating labeled compounds for diagnostic imaging and in vitro testing kits.
• Chemical Synthesis: Acts as a versatile intermediate for introducing iodinated aromatic structures into more complex molecules in organic synthesis.

Basic Information

Product Name	Hydroxy-[4-(4-Hydroxy-3,5-Diiodo-Phenoxy)]-3,5-Diiodophenylacetic Acid
CAS No.	93647-48-4
Molecular Formula	C14H8I4O5
Molecular Weight	773.83 g/mol
Synonyms	3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)phenylacetic acid; 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid; 4-[4-Hydroxy-3,5-diiodophenoxy]-3,5-diiodophenylacetic acid; 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)hydrocinnamic acid (related); Thyroxine intermediate; T4 synthetic intermediate; Iodinated diphenyl ether derivative
EINECS	Contact for details

Quality Control

Our Hydroxy-[4-(4-Hydroxy-3,5-Diiodo-Phenoxy)]-3,5-Diiodophenylacetic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. We adhere to in-house specifications aligned with ICH guidelines for impurities. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.