Description

2,4,10-Trioxatricyclo[3.3.1.13,7]Decane-3-Carbonyl Chloride (9Ci) is a highly reactive and versatile acyl chloride derivative of a tricyclic orthoester. This compound is valued as a critical building block in advanced organic synthesis, enabling the efficient introduction of a complex, functionalized framework. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures, particularly in medicinal chemistry programs targeting new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those requiring rigid, polycyclic scaffolds for enhanced binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where its unique structure can impart specific biological activity.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored thermal or chemical properties.
• Ligand and Catalyst Development: Employed for constructing sophisticated chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create activity-based probes or labeled compounds for studying biological pathways and enzyme functions.

Basic Information

Product Name	2,4,10-Trioxatricyclo[3.3.1.13,7]Decane-3-Carbonyl Chloride (9Ci)
CAS No.	93563-95-2
Molecular Formula	C8H9ClO4
Molecular Weight	204.61 g/mol
Synonyms	1-Adamantanecarbonyl chloride, 3-oxa-5,7-dioxo-; 3-Carboxy-1-adamantyl chloride orthoformate; Tricyclo[3.3.1.13,7]decane-1-carbonyl chloride, 3-oxa-5,7-dioxo-; 2,4,10-Trioxatricyclo[3.3.1.13,7]decane-3-carbonyl chloride; 1-Adamantanecarbonyl chloride cyclic orthoformate
EINECS	Contact for details

Quality Control

Every batch of 2,4,10-Trioxatricyclo[3.3.1.13,7]Decane-3-Carbonyl Chloride (9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.