Description

3-Amino-3-Hydroxycarbonyl-1-n-Cbz Pyrrolidine is a high-purity, protected pyrrolidine derivative serving as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the design and construction of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Peptidomimetics: Serves as a constrained proline analog for the development of peptide-based therapeutics with enhanced metabolic stability.
• Asymmetric Catalysis Ligand Precursor: Can be utilized in the preparation of chiral ligands for catalytic asymmetric transformations.
• Agrochemical Synthesis: Employed as a building block for creating novel, biologically active compounds in crop protection research.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and chemical biology studies.

Basic Information

Product Name	3-Amino-3-Hydroxycarbonyl-1-n-Cbz Pyrrolidine
CAS No.	93533-01-8
Molecular Formula	C13H16N2O4
Molecular Weight	264.28 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-amino-3-carboxypyrrolidine; 3-Amino-3-carboxy-1-Cbz-pyrrolidine; 1-Cbz-3-amino-3-carboxypyrrolidine; (3-Amino-3-carboxypyrrolidin-1-yl)(phenyl)methanone N-benzyl carbamate derivative; 3-Amino-1-(benzyloxycarbonyl)pyrrolidine-3-carboxylic acid; N-Carbobenzoxy-3-amino-3-carboxypyrrolidine; Z-3-Amino-3-carboxypyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Amino-3-Hydroxycarbonyl-1-n-Cbz Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.