Description

2-(3,5-Bis(Trifluoromethyl)Phenyl)Ethanol is a high-value fluorinated aromatic building block, essential for introducing lipophilic and electron-withdrawing trifluoromethylphenyl groups into complex molecular architectures. Its primary value lies in enabling the synthesis of advanced pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine or nitrogen-based ligands used in asymmetric catalysis.
• Advanced Material Precursor: Employed in the research and development of liquid crystals, organic semiconductors, and polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for client-specific molecules.
• Academic & Industrial Research: Used in exploratory chemistry to study structure-activity relationships (SAR) and develop new synthetic methodologies involving fluorinated arenes.

Basic Information

Product Name	2-(3,5-Bis(Trifluoromethyl)Phenyl)Ethanol
CAS No.	93427-28-2
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]ethanol; 2-(3,5-Bis(trifluoromethyl)phenyl)ethan-1-ol; 3,5-Bis(trifluoromethyl)phenethyl alcohol; 2-(3,5-Di(trifluoromethyl)phenyl)ethanol; α-(3,5-Bis(trifluoromethyl)phenyl)ethanol; (3,5-Bis(trifluoromethyl)phenyl)ethanol; 93427-28-2; 3,5-Bis(trifluoromethyl)benzeneethanol
EINECS	Contact for details

Quality Control

Our 2-(3,5-Bis(Trifluoromethyl)Phenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Purity (HPLC/GC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.