Description

3-Isoxazolemethanol,5-(Chloromethyl)--α--Methyl-,(-)-(9Ci) is a specialized chiral isoxazole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both chloromethyl and hydroxymethyl functional groups on the heterocyclic core, makes it a valuable building block for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the isoxazole moiety's bioactivity.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways due to its reactive handles.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of novel polymers with specific optical or electronic properties.
• Asymmetric Catalysis Ligand Synthesis: Utilized in the preparation of chiral ligands for asymmetric catalysis, essential for producing enantiomerically pure compounds.

Basic Information

Product Name	3-Isoxazolemethanol,5-(Chloromethyl)--α--Methyl-,(-)-(9Ci)
CAS No.	93422-82-3
Molecular Formula	C6H8ClNO2
Molecular Weight	161.59 g/mol
Synonyms	(-)-5-(Chloromethyl)-α-methyl-3-isoxazolemethanol; (S)-5-(Chloromethyl)-α-methyl-3-isoxazolemethanol; 3-Isoxazolemethanol, 5-(chloromethyl)-α-methyl-, (-)-; 5-(Chloromethyl)-α-methyl-3-isoxazolemethanol (9CI); (S)-5-(Chloromethyl)-3-(1-hydroxyethyl)isoxazole; 93422-82-3; (S)-5-(Chloromethyl)-3-(hydroxymethyl)isoxazole derivative
EINECS	Contact for details

Quality Control

Our 3-Isoxazolemethanol,5-(Chloromethyl)--α--Methyl-,(-)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.