Description

Botulinum Toxin CAS NO 93384-43-1 is a potent neurotoxic protein produced by the bacterium *Clostridium botulinum*. This highly purified biological agent is critical for therapeutic and cosmetic applications due to its ability to temporarily inhibit muscle contractions. It is an essential active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical, biotechnology, and advanced aesthetic medicine sectors.

Application

• Therapeutic Pharmaceutical Formulations: Primary API for injectable drugs treating chronic migraine, cervical dystonia, blepharospasm, strabismus, and severe axillary hyperhidrosis.
• Aesthetic Medicine: Core ingredient in cosmetic injectables for the temporary reduction of moderate to severe frown lines, crow's feet, and forehead lines.
• Neurological Research: Used as a precise tool in neuroscience research to study synaptic transmission, neuronal function, and muscle physiology.
• Bioprocessing & Development: Serves as a reference standard in quality control laboratories for assay validation and the development of new biologic entities.

Basic Information

Product Name	Botulinum Toxin
CAS No.	93384-43-1
Molecular Formula	C6760H10447N1743O2010S32
Molecular Weight	~149 kDa (Botulinum Neurotoxin Type A complex)
Synonyms	Botulinum Neurotoxin Type A; BTX-A; BoNT/A; OnabotulinumtoxinA; Clostridium Botulinum Type A Neurotoxin; Botox (Trade Name); Dysport (Trade Name); Xeomin (Trade Name)
EINECS	Contact for details

Quality Control

Our Botulinum Toxin is manufactured under strict cGMP conditions, ensuring the highest standards of purity, potency, and safety. Each batch is subjected to a comprehensive battery of tests including potency assay (LD50), protein content, purity by HPLC, sterility, endotoxin levels, and identity confirmation. Certificates of Analysis (COA) documenting compliance with relevant pharmacopoeial standards (e.g., USP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive) and must be handled under controlled conditions to maintain potency.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or crystalline solid
Identification (HPLC/Activity)	Conforms to reference standard
Potency (Specific Activity)	> 1.0 x 108 U/mg protein
Purity (SDS-PAGE / HPLC)	> 95% (as neurotoxin complex)
Protein Content (Lowry)	Specified per batch
Endotoxin	< 5.0 EU/mg
Sterility	Sterile (meets USP <71> requirements)
Moisture Content (KF)	< 3.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.