Description

Icotidine is a selective histamine H2-receptor antagonist with significant research and development applications. This compound is valued for its role in studying gastric acid secretion and related physiological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and chemical manufacturers developing novel therapeutic agents. The material is supplied to meet the stringent purity requirements of advanced scientific and industrial applications.

Application

• Pharmaceutical Research & Development: A key intermediate or reference standard in the discovery and development of new H2-receptor antagonists and gastroprotective agents.
• Biochemical Studies: Used as a pharmacological tool to investigate the role of histamine H2 receptors in various in vitro and in vivo experimental models.
• Academic Research: Employed in university and institutional labs for fundamental studies on receptor pharmacology and signal transduction mechanisms.
• Chemical Synthesis: Serves as a building block for the synthesis of more complex molecules or analogs in medicinal chemistry programs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical substances.

Basic Information

Product Name	Icotidine
CAS No.	93376-90-0
Molecular Formula	C13H19N5O3S
Molecular Weight	325.39 g/mol
Synonyms	Icotidine; SK&F 93319; 2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N2-cyano-N-ethylacetamidine; 2-({[2-(Carbamimidamido)-1,3-thiazol-4-yl]methyl}sulfanyl)-N-cyano-N'-ethylacetamidine; N-Cyano-N'-[2-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]ethyl]-N-ethylguanidine
EINECS	Contact for details

Quality Control

Our Icotidine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot. We are committed to supplying materials that support reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions that minimize exposure to moisture and temperature fluctuations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.