Description

2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Isothiocyanate is a high-purity, protected glycosyl donor derivative, essential for the stereoselective synthesis of complex carbohydrate mimetics and thioglycosides. Its core value lies in enabling precise chemical modifications in carbohydrate chemistry, which is critical for developing novel pharmaceuticals and bioactive compounds. This advanced intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of glycoconjugates, antiviral agents, and diagnostic probes.

Application

• Glycoconjugate Synthesis: A key building block for the preparation of neoglycoproteins, glycolipids, and other complex carbohydrate derivatives for biological studies.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutics, particularly in antiviral and anticancer drug discovery programs.
• Carbohydrate Mimetics: Facilitates the synthesis of stable glycomimetics that mimic natural sugars for use in biochemical assays and inhibitor design.
• Thioglycoside Preparation: Serves as a versatile precursor for synthesizing various thioglycosides, which are valuable tools in glycoscience.
• Chemical Biology Probes: Enables the creation of labeled carbohydrate probes for studying carbohydrate-protein interactions and metabolic pathways.
• Academic & Industrial Research: A critical reagent for synthetic organic chemists in both academic laboratories and R&D departments focusing on glycosylation methodologies.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Isothiocyanate
CAS No.	93221-21-7
Molecular Formula	C15H19NO9S
Molecular Weight	389.38 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl isothiocyanate; 1-Isothiocyanato-2,3,4,6-tetra-O-acetyl-α-D-mannopyranose; α-D-Mannopyranosyl isothiocyanate, 2,3,4,6-tetraacetate; Tetraacetylmannosyl isothiocyanate; Ac4ManNCS; 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl mustard oil; Peracetylated α-D-mannosyl isothiocyanate
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Isothiocyanate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.