Description

4-Bromo-1-Benzothiophene-2-Carbonyl Chloride is a high-value, reactive organic intermediate characterized by its benzothiophene core and functional acid chloride group. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science, where it serves as a key building block for introducing the 4-bromobenzothiophene moiety. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

This versatile intermediate is a critical precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the benzothiophene scaffold for biological activity.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as semiconductors and light-emitting compounds for OLED research.
• Chemical Research & Development: Acts as a versatile reagent for introducing functionalized benzothiophene units into more complex molecular architectures in academic and industrial labs.
• Ligand Synthesis: Utilized for preparing specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-1-Benzothiophene-2-Carbonyl Chloride
CAS No.	93104-01-9
Molecular Formula	C9H4BrClOS
Molecular Weight	275.55 g/mol
Synonyms	4-Bromobenzo[b]thiophene-2-carbonyl chloride; 4-Bromo-1-benzothiophene-2-carboxylic acid chloride; 2-Carbonyl chloride-4-bromobenzothiophene; 4-Bromobenzo[b]thien-2-yl carbonyl chloride; 93104-01-9; 4-Bromo-benzo[b]thiophene-2-carbonyl chloride; 4-Bromothianaphthene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Benzothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality supports applications in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.