Description

2-Azetidinecarbonyl Chloride, 1,4-Dimethyl-, cis- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride group on a constrained azetidine ring. This compound matters as a key chiral synthon for introducing the cis-dimethylazetidine moiety into complex molecular architectures, enabling the synthesis of novel pharmacophores and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing nitrogen-containing heterocycles with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used to create advanced pesticide and herbicide molecules with improved efficacy and selectivity.
• Chiral Ligand & Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific chemical and physical properties.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & R&D Laboratories: Utilized in fundamental research to explore new chemical reactions and develop new synthetic methodologies.

Basic Information

Product Name	2-Azetidinecarbonyl Chloride, 1,4-Dimethyl-, cis- (9Ci)
CAS No.	92735-69-8
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	cis-1,4-Dimethylazetidine-2-carbonyl chloride; (2S,4R)-1,4-Dimethylazetidine-2-carbonyl chloride; 1,4-Dimethyl-2-azetidinecarbonyl chloride, cis-; cis-2-(Chlorocarbonyl)-1,4-dimethylazetidine; Azetidine-2-carbonyl chloride, 1,4-dimethyl-, cis-
EINECS	Contact for details

Quality Control

Our 2-Azetidinecarbonyl Chloride, 1,4-Dimethyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and highly volatile. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to minimize evaporation. Store away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.