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2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucose CAS NO 92659-90-0


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CAS No.:92659-90-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucose is a chemically modified monosaccharide derivative, specifically a glucose analog functionalized with an azidoacetyl group. This compound is of significant value as a versatile biochemical tool and a key intermediate in click chemistry and metabolic glycoengineering applications. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel diagnostics, probes, and targeted therapeutics.

Application

  • Metabolic Glycoengineering (MGE): Acts as a metabolic precursor for incorporating azide tags into cell surface glycans, enabling subsequent bioorthogonal labeling (e.g., via click chemistry with alkynes).
  • Chemical Biology & Proteomics: Used as a building block for synthesizing activity-based probes (ABPs) to study glycosidase enzymes and carbohydrate-processing pathways.
  • Glycoconjugate Synthesis: Serves as a key intermediate in the synthesis of complex oligosaccharides, glycopeptides, and glycoproteins for immunological and drug discovery research.
  • Antiviral & Cancer Research: Investigated for its potential to interfere with glycosylation processes in viruses and cancer cells, exploring novel therapeutic mechanisms.
  • Diagnostic Agent Development: Utilized in the creation of contrast agents and molecular imaging probes for PET, MRI, or fluorescence imaging.
  • Material Science: Applied in the surface functionalization of nanomaterials and polymers to create bioactive coatings and smart materials.

Basic Information

Item Detail
Product Name 2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucose
CAS No. 92659-90-0
Molecular Formula C8H14N4O6
Molecular Weight 262.22 g/mol
Synonyms 2-Azidoacetamido-2-deoxy-D-glucose; N-(Azidoacetyl)glucosamine; 2-Deoxy-2-[(azidoacetyl)amino]-D-glucopyranose; AcGlcNAz; 2-Azidoacetamido-2-deoxy-D-glucopyranose; Metabolic precursor for Ac4GlcNAz; N-Azidoacetyl-D-glucosamine; Azidoacetyl glucosamine
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Quality Control

Our 2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥95%
Water Content (KF) ≤5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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