Description

Cyclohexanecarbonyl Chloride, 5-Chloro-2-Methyl-, (1Alpha,2Beta,5Beta)- (9Ci) is a specialized chiral building block and acid chloride derivative of significant value in advanced organic synthesis. Its precise stereochemistry and reactive functional group make it a critical intermediate for constructing complex, high-value molecules with defined spatial configurations. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and selectivity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereoisomers.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique structural properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 5-Chloro-2-Methyl-, (1Alpha,2Beta,5Beta)- (9Ci)
CAS No.	92284-41-8
Molecular Formula	C8H12Cl2O
Molecular Weight	195.09 g/mol
Synonyms	(1R,2S,5R)-5-Chloro-2-methylcyclohexanecarbonyl chloride; (1α,2β,5β)-5-Chloro-2-methylcyclohexanecarboxylic acid chloride; 5-Chloro-2-methylcyclohexanecarbonyl chloride (stereoisomer); rel-(1R,2S,5R)-5-Chloro-2-methylcyclohexanecarbonyl chloride; Cyclohexanecarboxylic acid, 5-chloro-2-methyl-, chloride, (1α,2β,5β)-; Chiral Cyclohexanecarbonyl Chloride Derivative
EINECS	Contact for details

Quality Control

Every batch of our Cyclohexanecarbonyl Chloride, 5-Chloro-2-Methyl-, (1Alpha,2Beta,5Beta)- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% de (diastereomeric excess)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.