Description

9-(3'-Azido-3'-Deoxy-β-Xylofuranosyl)Guanine 5'-Triphosphate is a specialized nucleoside triphosphate analog, a critical building block for biochemical research and pharmaceutical development. This compound is engineered to act as a chain terminator or probe in enzymatic studies, particularly those involving DNA/RNA polymerases and reverse transcriptases. It is essential for researchers and manufacturers in nucleic acid chemistry, antiviral drug discovery, and molecular diagnostics, where precise control over nucleic acid synthesis is required.

Application

• Antiviral Drug Development: Used as a substrate analog to study and inhibit viral polymerases, aiding in the discovery of novel antiviral agents.
• Molecular Biology Research: Acts as a chain-terminating nucleotide in sequencing applications and polymerase chain reaction (PCR) studies.
• Biochemical Probe Synthesis: Incorporated into oligonucleotides to create labeled probes for studying nucleic acid-protein interactions and enzyme mechanisms.
• Enzyme Kinetics Studies: Serves as a substrate to investigate the kinetics and fidelity of DNA and RNA polymerases.
• Diagnostic Assay Development: Utilized in the design of diagnostic kits for detecting viral loads and genetic mutations.
• Nucleic Acid Chemistry: A key intermediate in the synthesis of modified nucleotides and oligonucleotide conjugates for therapeutic applications.

Basic Information

Item	Information
Product Name	9-(3'-Azido-3'-Deoxy-β-Xylofuranosyl)Guanine 5'-Triphosphate
CAS No.	92117-26-5
Molecular Formula	C15H21N8O13P3
Molecular Weight	614.32 g/mol
Synonyms	3'-Azido-3'-deoxyguanosine 5'-triphosphate; 3'-Azido-3'-deoxy-GTP; N3-Azido-N3-deoxyguanosine triphosphate; 9-[(3-Azido-3-deoxy-β-D-xylofuranosyl)]guanine 5'-triphosphate; Azidodeoxyguanosine triphosphate; 3'-N3-dGTP; Chain-terminating GTP analog; Anti-HIV nucleotide analog
EINECS	Contact for details

Quality Control

Our 9-(3'-Azido-3'-Deoxy-β-Xylofuranosyl)Guanine 5'-Triphosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support compliance with cGMP guidelines for advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.