Description

9-(3'-Azido-3'-Deoxyxylofuranosyl)Adenine 5'-Monophosphate is a chemically modified nucleoside monophosphate analog, a key building block in advanced biochemical research and development. This compound is valued for its role as a versatile intermediate in the synthesis of novel nucleotide-based therapeutics and diagnostic probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, oligonucleotide synthesis, and the development of click chemistry-compatible molecular tools.

Application

• Antiviral Research: Serves as a crucial intermediate in the synthesis of nucleoside analogs for investigating novel mechanisms against viral replication.
• Oligonucleotide Synthesis: Used as a modified phosphoramidite precursor for incorporating azide-functionalized nucleotides into DNA/RNA strands for labeling and conjugation.
• Click Chemistry Reagents: The azido group enables efficient, bioorthogonal copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe development.
• Biochemical Probe Development: Facilitates the creation of activity-based probes for studying enzyme mechanisms, particularly kinases and polymerases.
• Medicinal Chemistry: Acts as a scaffold for structure-activity relationship (SAR) studies in the design of new therapeutic agents.
• Diagnostic Assay Development: Employed in the fabrication of sensitive detection systems through its specific, clickable functional group.

Basic Information

Product Name	9-(3'-Azido-3'-Deoxyxylofuranosyl)Adenine 5'-Monophosphate
CAS No.	92117-24-3
Molecular Formula	C15H19N8O7P
Molecular Weight	454.34 g/mol
Synonyms	3'-Azido-3'-deoxyxylofuranosyladenine 5'-monophosphate; 3'-Azidoadenosine 5'-monophosphate (xylo configuration); 9-[(3-Azido-3-deoxy-β-D-xylofuranosyl)]adenine 5'-monophosphate; 3'-N3-xylo-Adenosine 5'-monophosphate; Azidonucleotide Monophosphate; 3'-Azido-3'-deoxyxylo-AMP; ADENINE, 9-(3-AZIDO-3-DEOXY-.BETA.-D-XYLOFURANOSYL)-, 5'-(DIHYDROGEN PHOSPHATE)
EINECS	Contact for details

Quality Control

Our 9-(3'-Azido-3'-Deoxyxylofuranosyl)Adenine 5'-Monophosphate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.