Description

(22R)-6α,7α-Epoxy-5,12α,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid 26,22-Lactone is a complex ergostane-type steroidal lactone, a key structural motif and intermediate in the synthesis of bioactive natural products. This compound matters for its role as a critical building block in advanced pharmaceutical research and development, particularly for exploring novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on steroid chemistry, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex steroidal drugs and investigational new chemical entities.
• Biochemical Research: Used as a reference standard or a starting material in studies exploring sterol biosynthesis pathways and enzyme inhibition.
• Natural Product Synthesis: A key scaffold for the semi-synthesis or total synthesis of ergostane-derived natural products with potential biological activity.
• Academic Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.
• API Development: Investigated as an intermediate in the development of Active Pharmaceutical Ingredients (APIs) targeting specific receptors.

Basic Information

Item	Detail
Product Name	(22R)-6α,7α-Epoxy-5,12α,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid 26,22-Lactone
CAS No.	92070-79-6
Molecular Formula	C28H36O7
Molecular Weight	484.59 g/mol
Synonyms	6α,7α-Epoxy-5,12α,22-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid 26,22-lactone; (22R)-Ergosta-2,24-dien-26-oic acid lactone derivative; Steroidal epoxy lactone; Ergostane lactone intermediate; 92070-79-6; UNII-9H0S6Y4F8B; 5α-Ergosta-2,24-dien-26-oic acid, 6α,7α-epoxy-5,12α,22-trihydroxy-1-oxo-, 26,22-lactone, (22R)-
EINECS	Contact for details

Quality Control

Our (22R)-6α,7α-Epoxy-5,12α,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid 26,22-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate to ensure long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.