Description

3-[3-[[2-(3,4-Dimethoxyphenyl)Ethyl]Methylamino]Propyl]-1,3,4,5-Tetrahydro-7,8-Dimethoxy-2H-3-Benzazepin-2-One Hydrochloride is a high-purity, complex organic compound supplied as a hydrochloride salt, offering enhanced stability and handling properties. This compound serves as a critical advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential central nervous system (CNS) active compounds and receptor ligands.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Research: Serves as a reference standard or tool compound in pharmacological assays and receptor binding studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and neuropharmacology research.

Basic Information

Item	Details
Product Name	3-[3-[[2-(3,4-Dimethoxyphenyl)Ethyl]Methylamino]Propyl]-1,3,4,5-Tetrahydro-7,8-Dimethoxy-2H-3-Benzazepin-2-One Hydrochloride
CAS No.	91940-87-3
Molecular Formula	C27H39ClN2O5
Molecular Weight	507.06 g/mol
Synonyms	Fenoldopam Impurity; Fenoldopam Related Compound; 1-(3,4-Dimethoxyphenyl)-5,6-dihydroxy-2,3,7,8-tetrahydro-1H-3-benzazepine Hydrochloride (related structure); SK&F 82526-J; Benzazepine derivative; Corlopam Impurity; 7,8-Dimethoxy-1-(3,4-dimethoxyphenethyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ol Hydrochloride (alternative naming)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ validated analytical methods, including HPLC and NMR, to ensure compliance with client specifications and research-grade standards. Quality systems are designed to support both non-GMP and cGMP manufacturing requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.