Description

N(4)-Methoxydeoxycytidine 5'-Phosphate is a chemically modified nucleotide monophosphate, specifically a derivative of deoxycytidine. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a building block for modified oligonucleotides. It is primarily utilized by researchers in nucleic acid chemistry, medicinal chemistry, and molecular biology for applications requiring precise structural modifications to DNA.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of modified DNA strands.
• Antisense & siRNA Research: Used to incorporate stable modifications into therapeutic oligonucleotides to enhance nuclease resistance and binding affinity.
• Structural Biology Studies: Serves as a probe to investigate DNA-protein interactions and enzyme mechanisms involving cytidine modification.
• Pharmaceutical Intermediate: An important synthetic intermediate in the development of nucleoside-based antiviral or anticancer prodrugs.
• Diagnostic Probe Development: Employed in the creation of labeled DNA probes for sensitive detection and diagnostic assays.

Basic Information

Product Name	N(4)-Methoxydeoxycytidine 5'-Phosphate
CAS No.	91886-20-3
Molecular Formula	C10H16N3O8P
Molecular Weight	337.23 g/mol
Synonyms	4-Methoxy-2'-deoxycytidine 5'-monophosphate; 5'-dCMP(4-OMe); 2'-Deoxy-4-methoxycytidine 5'-phosphate; N4-Methoxy-2'-deoxycytidine 5'-monophosphate; 5'-O-Phosphono-2'-deoxy-N4-methoxycytidine; dC(4OMe)MP; Modified Deoxycytidine Monophosphate
EINECS	Contact for details

Quality Control

Our N(4)-Methoxydeoxycytidine 5'-Phosphate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards to meet the demands of pharmaceutical research and molecular biology. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.