Description

Spiro[3.5]Nonane-2-Carbonyl Chloride (7Ci) is a specialized spirocyclic acid chloride building block, essential for introducing the unique, rigid spiro[3.5]nonane scaffold into target molecules. Its high reactivity enables efficient amide and ester bond formation, making it a critical intermediate for advanced research and development. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by material scientists exploring new polymers and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the spirocyclic structure for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling and modifying biomolecules in probe and linker synthesis.
• Ligand & Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	Spiro[3.5]Nonane-2-Carbonyl Chloride (7Ci)
CAS No.	91716-33-5
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	Spiro[3.5]nonane-2-carbonyl chloride; 2-Carboxyspiro[3.5]nonane chloride; 7CI; Spiro(3,5)nonane-2-carboxylic acid chloride; 2-Carbonylchlorospiro[3.5]nonane; Spiro[3.5]nonane-2-carboxylic acid chloride; 2-(Chlorocarbonyl)spiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our Spiro[3.5]Nonane-2-Carbonyl Chloride (7Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.