Description

(S)-Bifonazole CAS NO 91487-86-4 is the single enantiomer of the broad-spectrum antifungal agent Bifonazole, offering a high degree of stereochemical purity for advanced pharmaceutical research and development. This compound is critical for studying structure-activity relationships and developing more potent, selective antifungal therapies with potentially improved pharmacokinetic profiles. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focusing on enantioselective synthesis and novel antifungal drug candidates.

Application

• As a key chiral intermediate in the research and development of novel enantiopure antifungal pharmaceuticals.
• For biological activity studies to investigate the specific efficacy and toxicity profile of the (S)-enantiomer compared to the racemic mixture.
• Use in method development and validation for analytical techniques like chiral HPLC to separate and quantify enantiomers.
• As a reference standard in quality control laboratories for ensuring the stereochemical purity of antifungal API batches.
• Fundamental research in medicinal chemistry to understand the interaction between specific enantiomers and fungal enzyme targets.
• Potential use in veterinary medicine R&D for targeted antifungal treatments.

Basic Information

Product Name	(S)-Bifonazole
CAS No.	91487-86-4
Molecular Formula	C22H18N2
Molecular Weight	310.40 g/mol
Synonyms	(S)-1-[(R)-Biphenyl-4-yl(phenyl)methyl]-1H-imidazole; (S)-Bifonazole; (S)-α-(4-Biphenylyl)phenyl-1H-imidazole-1-methanol; (S)-Enantiomer of Bifonazole; (-)-Bifonazole; (S)-Mycospor; Bifonazole S-Enantiomer
EINECS	Contact for details

Quality Control

Our (S)-Bifonazole is produced under strict quality management systems to ensure high stereochemical and chemical purity suitable for research applications. Each batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity and enantiomeric excess (e.e.). A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.