Description

5'-Methylthioformycin is a chemically modified nucleoside analog, a derivative of the natural antibiotic formycin. This compound is of significant interest in biochemical and pharmaceutical research due to its structural similarity to adenosine and its potential to act as a substrate or inhibitor for various enzymes. It serves as a valuable building block and research tool for scientists in medicinal chemistry and enzymology. Key users include research institutions and pharmaceutical companies focused on developing novel antiviral or anticancer agents, as well as those studying purine metabolism and nucleoside transport mechanisms.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for adenosine deaminase and other purine-metabolizing enzymes.
• Medicinal Chemistry: Serves as a key intermediate or precursor in the synthesis of novel nucleoside-based pharmaceutical candidates.
• Antiviral/Anticancer Agent Development: Investigated for its potential biological activity and mechanism of action in cell-based assays.
• Enzyme Mechanism Probes: Utilized to study enzyme kinetics, binding sites, and catalytic pathways due to its modified structure.
• Nucleoside Metabolism Studies: Acts as a tool compound to investigate cellular uptake, phosphorylation, and the metabolic fate of nucleoside analogs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC or LC-MS analysis.

Basic Information

Product Name	5'-Methylthioformycin
CAS No.	91255-90-2
Molecular Formula	C12H15N5O4S
Molecular Weight	325.34 g/mol
Synonyms	5'-(Methylthio)formycin; 5'-Deoxy-5'-(methylthio)formycin; 7-Amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine-5'-methyl sulfide; Formycin 5'-methyl thioether; MTF
EINECS	Contact for details

Quality Control

Our 5'-Methylthioformycin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade material standards. Specifications are designed to meet the exacting requirements of advanced pharmaceutical R&D and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccants and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.