Description

4-Azidoaniline Hydrochloride is a versatile aromatic amine derivative, primarily valued as a key chemical building block for click chemistry and bioconjugation applications. Its reactive azido group enables efficient, selective, and bioorthogonal coupling with alkynes, making it indispensable for advanced material and life science research. This compound is critical for researchers and manufacturers in pharmaceutical development, polymer science, and the synthesis of fluorescent probes and functional materials.

Application

• Click Chemistry Reagent: Serves as a fundamental precursor for synthesizing azide-functionalized molecules used in Huisgen 1,3-dipolar cycloaddition reactions.
• Bioconjugation & Probe Synthesis: Used to label biomolecules (proteins, antibodies, nucleic acids) with fluorescent dyes, affinity tags, or other functional groups for imaging and diagnostic applications.
• Polymer & Material Science: Incorporated into polymer backbones or surfaces to introduce reactive sites for cross-linking, surface modification, and creating smart materials.
• Pharmaceutical Intermediate: Acts as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Utilized in the synthesis of novel compounds for crop protection and agricultural chemical development.
• Cross-linking Agent: Functions as a photoactivatable or thermally activatable cross-linker for modifying proteins and other macromolecular structures.

Basic Information

Product Name	4-Azidoaniline Hydrochloride
CAS No.	91159-79-4
Molecular Formula	C6H7N4Cl
Molecular Weight	170.60 g/mol
Synonyms	p-Azidoaniline Hydrochloride; 4-Aminophenyl Azide Hydrochloride; 1-Azido-4-aminobenzene Hydrochloride; Benzenamine, 4-azido-, hydrochloride; 4-Azidobenzenamine Hydrochloride; Aniline, p-azido-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Azidoaniline Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Light yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.