Description

(5R)-5β-Acetoxy-4α-[[(3Aα,8Aα)-Decahydro-1,4,4-Trimethyl-8-Methyleneazulen]-1α-Yl]Tetrahydrofuro[2,3-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a crucial advanced intermediate in the synthesis of novel bioactive molecules and complex natural product analogs. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process development, and the exploration of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates with potential anti-inflammatory or anticancer activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new pharmacophores based on sesquiterpene scaffolds.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for complex natural products or their derivatives.
• Academic Research: Employed in organic synthesis laboratories for methodological studies and the total synthesis of complex molecules.
• Biochemical Probe Development: Potential precursor for creating labeled compounds or probes to study biological pathways.
• Fine Chemical Synthesis: Intermediate in the multi-step production of specialty chemicals and high-value fragrance ingredients.

Basic Information

Product Name	(5R)-5β-Acetoxy-4α-[[(3Aα,8Aα)-Decahydro-1,4,4-Trimethyl-8-Methyleneazulen]-1α-Yl]Tetrahydrofuro[2,3-B]Furan-2(3H)-One
CAS No.	91158-68-8
Molecular Formula	C25H34O5
Molecular Weight	414.53 g/mol
Synonyms	4α-[(1α,3aα,4α,7aα)-Decahydro-1,4,4-trimethyl-8-methyleneazulen-1-yl]-5β-acetoxytetrahydrofuro[2,3-b]furan-2(3H)-one; (5R)-5β-Acetoxy-4α-[(1α,3aα,4α,7aα)-decahydro-1,4,4-trimethyl-8-methyleneazulen-1-yl]tetrahydrofuro[2,3-b]furan-2(3H)-one; 5β-Acetoxy-4α-[(1α,3aα,4α,7aα)-decahydro-1,4,4-trimethyl-8-methyleneazulen-1-yl]tetrahydrofuro[2,3-b]furan-2(3H)-one; A sesquiterpene lactone acetate derivative.
EINECS	Contact for details

Quality Control

Our (5R)-5β-Acetoxy-4α-[[(3Aα,8Aα)-Decahydro-1,4,4-Trimethyl-8-Methyleneazulen]-1α-Yl]Tetrahydrofuro[2,3-B]Furan-2(3H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be considered light-sensitive and moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.