Description

(2R,3R,4R,5R)-5-(6-Amino-1-Methyl-2H-Purin-9-Yl)-2-(Hydroxymethyl)-4-M Ethoxy-Oxolan-3-Ol is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where precise stereochemistry is paramount for biological activity. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside-based antiviral drugs and chemotherapeutic agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Pro-drug Development: Serves as a modified nucleoside backbone for creating targeted pro-drugs with enhanced bioavailability.
• Diagnostic Reagent Synthesis: Employed in the manufacture of labeled compounds for molecular diagnostics and imaging.
• Life Science Tools: Component in the preparation of specialized reagents for genomics and molecular biology applications.
• Academic Research: Utilized in university and institutional labs for studying nucleic acid chemistry and medicinal chemistry.

Basic Information

Product Name	(2R,3R,4R,5R)-5-(6-Amino-1-Methyl-2H-Purin-9-Yl)-2-(Hydroxymethyl)-4-M Ethoxy-Oxolan-3-Ol
CAS No.	91101-00-7
Molecular Formula	C12H17N5O5
Molecular Weight	311.29 g/mol
Synonyms	1-Methyladenosine; N6-Methyladenosine (ambiguous, check isomer); 9-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1-methyl-1H-purin-6-amine; 1-Methyl-A; 1-MeA; 1-Methyladenosine (methyl ether derivative); 2'-Deoxy-1-methyladenosine analog (related structure); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this nucleoside analog is produced under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for pharmaceutical R&D and GMP starting materials. Specifications and COAs are available for review to ensure the material meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.