Description

Spiro(Androstan-3,2'-Oxiran)-17-One is a high-purity steroidal oxirane derivative, a key advanced intermediate in modern organic synthesis. This compound matters for its precise molecular architecture, enabling the targeted synthesis of complex steroid-based molecules with high regio- and stereoselectivity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and studying structure-activity relationships (SAR) in medicinal chemistry.
• Hormone Analog Synthesis: Serves as a precursor in the development of modified steroid hormones with potential therapeutic applications.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying steroid receptor interactions and signaling pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialized steroid derivatives.

Basic Information

Product Name	Spiro(Androstan-3,2'-Oxiran)-17-One
CAS No.	90991-90-5
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	17-Oxoandrostane-3-spiro-2'-oxirane; Androstan-17-one, 3,2'-epoxy- (8CI); 3,2'-Epoxyandrostan-17-one; 3,2'-Epoxy-5α-androstan-17-one; Spiro[androstane-3,2'-oxiran]-17-one; 5α-Androstan-17-one, 3,2'-epoxy-; Steroidal oxirane intermediate
EINECS	Contact for details

Quality Control

Our Spiro(Androstan-3,2'-Oxiran)-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.