Description

Cyclopropanecarbonyl Chloride, 2-Phenoxy- (6Ci,7Ci) CAS NO 90797-97-0 is a specialized organic intermediate featuring a reactive acid chloride group attached to a cyclopropane ring substituted with a phenoxy moiety. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of the cyclopropane pharmacophore, which is valued for its conformational rigidity and metabolic stability. Pharmaceutical, agrochemical, and advanced material research and development teams need this high-purity intermediate to create novel active ingredients and functional materials with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the cyclopropane ring can contribute to biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer Modification: Employed to introduce cyclopropane units into polymer backbones or side chains, potentially altering material properties like thermal stability, toughness, and chemical resistance.
• Chemical Biology Probe Development: Utilized in the creation of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Fine Chemical and Flavor/Fragrance Intermediate: Acts as a precursor in the multi-step synthesis of complex fine chemicals and aroma compounds.

Basic Information

Item	Detail
Product Name	Cyclopropanecarbonyl Chloride, 2-Phenoxy- (6Ci,7Ci)
CAS No.	90797-97-0
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	2-Phenoxycyclopropanecarbonyl chloride; (2-Phenoxycyclopropyl)carbonyl chloride; 2-Phenoxycyclopropane-1-carbonyl chloride; α-Phenoxycyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 2-phenoxy-; 1-Carboxy-2-phenoxycyclopropane chloride; (2-Phenoxy-1-cyclopropyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarbonyl Chloride, 2-Phenoxy- is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) and protected from moisture. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.