Description

(22R)-3β,14,20,22,27-Pentahydroxy-1-Oxoergosta-5,24-Dien-26-Oic Acid 26,22-Lactone CAS NO 90735-11-8 is a highly functionalized ergostane-type steroidal lactone, valued for its complex molecular architecture and biological relevance. This compound serves as a critical advanced intermediate or reference standard in pharmaceutical research and development, particularly for studying bioactive natural products. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical suppliers engaged in steroid chemistry, drug discovery, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Research Intermediate: A key building block for the synthesis of novel steroidal drugs and bioactive molecules.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroidal compounds.
• Biochemical Research: Investigated for its potential biological activities and interactions within metabolic or signaling pathways.
• Natural Product Synthesis: Serves as a sophisticated starting material or intermediate in the total synthesis of complex natural products.
• Academic Studies: Utilized in university and institutional research for exploring steroid chemistry and reaction mechanisms.

Basic Information

Product Name	(22R)-3β,14,20,22,27-Pentahydroxy-1-Oxoergosta-5,24-Dien-26-Oic Acid 26,22-Lactone
CAS No.	90735-11-8
Molecular Formula	C₂₈H₄₀O₇
Molecular Weight	488.62 g/mol
Synonyms	22R-Hydroxywithanolide E; (22R)-27-Hydroxywithanolide E; 3β,14,20,22,27-Pentahydroxy-1-oxoergosta-5,24-dien-26-oic acid 26,22-lactone; Withanolide analog; Ergosta-5,24-dien-26-oic acid derivative; Steroidal pentahydroxy lactone
EINECS	Contact for details

Quality Control

Our (22R)-3β,14,20,22,27-Pentahydroxy-1-Oxoergosta-5,24-Dien-26-Oic Acid 26,22-Lactone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.