Description

Cyclopentenyl Cytosine is a synthetic nucleoside analog with significant biochemical research applications. This compound matters as a potent and selective inhibitor of CTP synthetase, making it a valuable tool for studying nucleotide metabolism and cellular proliferation. Researchers in the fields of oncology, virology, and molecular biology need it for investigating novel therapeutic pathways and mechanisms of action.

Application

• Biochemical Research: Used as a specific inhibitor of CTP synthetase to study pyrimidine nucleotide biosynthesis and its regulation in cell cultures.
• Antiviral Studies: Investigated for its potential to inhibit the replication of DNA viruses by depleting intracellular cytidine triphosphate (CTP) pools.
• Oncology Research: Employed in preclinical studies to evaluate its antiproliferative effects on various cancer cell lines, leveraging its mechanism of nucleotide deprivation.
• Enzyme Kinetics: Serves as a substrate analog in enzymatic assays to characterize the activity and inhibition kinetics of CTP synthetase and related enzymes.
• Metabolic Pathway Analysis: A key tool for probing and mapping nucleotide salvage and *de novo* synthesis pathways in metabolic research.
• Pharmaceutical Intermediate: Acts as a sophisticated building block in the synthetic chemistry of novel nucleoside-based drug candidates.

Basic Information

Product Name	Cyclopentenyl Cytosine
CAS No.	90597-22-1
Molecular Formula	C9H13N3O4
Molecular Weight	227.22 g/mol
Synonyms	Cyclopentenylcytosine; Cyclopentenyl Cytidine; NSC 375575; (1S,4R)-4-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl)-2-cyclopentene-1-methanol; CPEC; CPE-Cytosine; 1-(2-Cyclopenten-1-ylmethyl)cytosine; 9-[(1S,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]guanine (common misnomer based on structure)
EINECS	Contact for details

Quality Control

Our Cyclopentenyl Cytosine is produced under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.