Description

Pyrazinecarbonyl Chloride, 3-Chloro- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its high reactivity makes it an indispensable reagent for introducing the 3-chloropyrazine-2-carbonyl moiety into target molecules, enabling the creation of complex structures with precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other heterocyclic drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate the pyrazine scaffold for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials, such as conductive polymers and organic semiconductors, where its structure imparts specific electronic properties.
• Peptide Mimetics and Bioconjugation: Useful for acylating amines in the creation of peptide analogs or for bioconjugation strategies in probe and linker molecule development.

Basic Information

Product Name	Pyrazinecarbonyl Chloride, 3-Chloro- (9Ci)
CAS No.	90361-99-2
Molecular Formula	C5H2Cl2N2O
Molecular Weight	176.99 g/mol
Synonyms	3-Chloropyrazine-2-carbonyl chloride; 2-Pyrazinecarbonyl chloride, 3-chloro-; 3-Chloro-2-pyrazinecarboxylic acid chloride; 3-Chloropyrazine-2-carboxylic acid chloride; 3-Chloro-2-pyrazinecarbonyl chloride; 3-Chloropyrazinecarbonyl chloride; 3-Chloro-2-carboxypyrazine chloride; 90361-99-2 (CAS)
EINECS	Contact for details

Quality Control

Every batch of Pyrazinecarbonyl Chloride, 3-Chloro- (9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development as well as scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation (by IR/FTIR), and impurity profile is provided with each shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.