Description

5-(2-Bromoethyl)-2'-Deoxyuridine is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound matters as a versatile building block and a key intermediate for the synthesis of more complex antiviral and anticancer agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside-based therapeutics and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidine kinase and other nucleoside-metabolizing enzymes.
• Pro-drug Development: Serves as a key intermediate for creating targeted pro-drugs designed for selective activation in tumor cells.
• Molecular Biology: Employed in the study of DNA synthesis, repair mechanisms, and for the development of labeled nucleotides.
• Antiviral Agent Synthesis: A building block for compounds being investigated for activity against herpesviruses and other DNA viruses.

Basic Information

Product Name	5-(2-Bromoethyl)-2'-Deoxyuridine
CAS No.	90301-64-7
Molecular Formula	C11H15BrN2O5
Molecular Weight	335.15 g/mol
Synonyms	5-(2-Bromoethyl)deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(2-bromoethyl)pyrimidine-2,4-dione; 5-Bromoethyl-2'-deoxyuridine; BrEdU; 5-(2-Bromoethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-5-(2-bromoethyl)uridine
EINECS	Contact for details

Quality Control

Our 5-(2-Bromoethyl)-2'-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and mass spectrometry are provided to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.