Description

5-(2-Hydroxyethyl)-2'-Deoxyuridine is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and research tool for investigating nucleoside metabolism and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral and anticancer drug discovery, as well as in advanced molecular biology studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to thymidine kinase and other nucleoside-metabolizing enzymes.
• Pro-drug Development: Investigated for the design of pro-drugs aimed at improving cellular uptake and therapeutic efficacy.
• Molecular Biology Tool: Employed in studies of DNA synthesis, repair mechanisms, and the function of modified nucleosides.
• Labeling Studies: Potential use in the synthesis of radiolabeled or fluorescently tagged compounds for tracking and imaging applications.

Basic Information

Product Name	5-(2-Hydroxyethyl)-2'-Deoxyuridine
CAS No.	90301-60-3
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	5-(2-Hydroxyethyl)deoxyuridine; 5-HEdU; 5-(2-Hydroxyethyl)-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(2-hydroxyethyl)pyrimidine-2,4-dione; 2'-Deoxy-5-(2-hydroxyethyl)uridine; 5-(2-Hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-(2-Hydroxyethyl)-2'-Deoxyuridine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, ensuring reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.